Digestive System (MED301) Course Detail

Course Name Course Code Season Lecture Hours Application Hours Lab Hours Credit ECTS
Digestive System MED301 5. Semester 6 1 1 6 0
Pre-requisite Course(s)
MED292
Course Language English
Course Type Compulsory Departmental Courses
Course Level Bachelor’s Degree (First Cycle)
Mode of Delivery Distance, Face To Face
Learning and Teaching Strategies Lecture, Discussion, Problem Solving, Team/Group.
Course Coordinator
Course Lecturer(s)
Course Assistants
Course Objectives To gain the knowledge about the development, structure and functions of the digestive system.
Course Learning Outcomes The students who succeeded in this course;
  • Lists the digestive system organs.
  • Describes the anterior abdominal wall and the inguinal canal.
  • Describes the location and function of the peritoneum.
  • Defines retroperitoneal and names the retroperitoneal organs.
  • Describes the function of the digestive system.
  • Describes stimuli and controls of digestive activity.
  • Defines the circulation of the digestive system organs.
  • Describes the macroscopic and microscopic anatomy and the basic functions of the mouth, salivary glands, pharynx, and esophagus.
  • Describes the composition and functions of saliva, and explains how salivation is regulated.
  • Defines the masticatory muscles, and explains the mechanisms of chewing and swallowing.
  • Defines the structure of the stomach.
  • Defines the cell types responsible for secreting the various components of gastric juice.
  • Defines the structure of the small intestine, and identifies its structural modifications that enhance the digestive process.
  • Differentiates between the various cell types of the intestinal mucosa.
  • Describes the function of local intestinal hormones and paracrines.
  • Describes the macroscopic and microscopic structure of the liver and bile ducts.
  • Describes the secretion of bile and the role of bile and gallbladder.
  • Describes the role of pancreatic juice in digestion.
  • Describes the structure and functions of the large intestine.
  • Describes the regulation of defecation.
  • Describes the regulation of defecation.
  • Lists the enzymes involved in digestion.
  • Describes the steps of protein, fat, carbohydrate and nucleic acid digestion.
  • Describes embryonic development of the digestive system.
  • Defines the gastrointestinal mucosal barrier.
  • Lists the infectious agents of digestive system, and describes their virulence, microbiological and epidemiological properties.
  • Explains the mechanisms of the diseases caused by the infectious agents and the methods of protection from these diseases.
  • Describes the sample management for microbiological diagnosis and microbiological diagnostic methods of infection agents, and interprets the results.
  • Describes the mechanism and causes of the common symptoms of the digestive system (nausea, vomiting, swallowing difficulty, reflux, dyspepsia, abdominal pain, bloating, diarrhea, constipation).
  • Explains the mechanisms and causes of jaundice.
  • Applies the basic occupational skills for the digestive system.
  • Defines etiologic factors, physiopathologic mechanisms, morphologic types involved in oral cavities, esophagus, stomch, bowel,liver, galbladder and pancreas
  • Describe physiopathologic mechanisms and morphologic changes, explain the importance of these mecanisms development in disease processes.
Course Content Anatomy and histology of digestive tracts; development of gastrointestinal organs; secretion of liver and pancreas, and regulaton of secretion; microorganisms causing infection in the digestive system; approach to patient with digestive system problem; diagnostic methods in digestive system diseases; gastrointestinal system bleedings.

Weekly Subjects and Releated Preparation Studies

Week Subjects Preparation
1 Introduction to Gastrointestinal System committee Temporal region and the muscles of mastication Oral cavity PBL Development of Digestive System and congenital malformations The anterior abdominal wall and inguinal canal The peritoneum, the lesser and greater omenta and the omental bursa Mouth digestion, chewing and swallowing; Digestion and absorption in the stomach Gastrointestinal System Physical Examination and Symptoms in Gastrointestinal Diseases Disorders of oral cavity & salivary glands Overview of glycolysis, gluconeogenesis, pentose phosphate pathway, glycogenesis, glycogenolysis, citric acid cycle and oxidative phosphorylation and ATP synthesis Esophagus: Obstructive and vascular diseases Pathology Abdominal part of oesophagus and stomach -
2 Enterobacteriaceae Pseudomonads, Acinetobacters and other Gram negative bacteria Emetic and antiemetic drugs Drugs That Aid Digestion PBL The small and large intestines Histology intestine and colon Vascular and obstructive disorders of the bowel Overview of glycolysis, gluconeogenesis, pentose phosphate pathway, glycogenesis, glycogenolysis, citric acid cycle and oxidative phosphorylation and ATP synthesis Inflammatory intestinal disease Gastrointestinal System Physical Examination and Symptoms in Gastrointestinal Diseases -
3 Polyps & tumors of small & large intestine The posterior abdominal wall and the great vessels Disorders & neoplasms of appendix & anal canal Esophagus, stomach, intestines The liver, biliary ducts, pancrea Digestive system histology: liver gallbladder pancreas Case Discusssion: Echinococcus Intestinal helmints Drug used in gastrointestinal disorders Control of food intake, basal metabolic rate and regulation of temperature Intestinal protozoa Intestinal Parasites The vessels, nerves of the digestive tract and portal system The posterior abdominal wall and the great vessels Bilirubin metabolism -
4 Approach to the Patient with Jaundice Introduction to liver function & diseases, liver failure Drug & toxin induced liver damage ( incl. Alcoholic liver disease), autoimmune hepatitis, metabolic liver diseases Cholestatic disorders(incl. Cholangiopathies, Billiary atresia) TBL: Acute Diarrhhea Hepatitis Viruses Acute hepatitis Antiprotozoal drugs Digestion and absorption of dietary fats Circulatory disorders of the liver Infectious diseases of the liver Hepatitis A and B vaccines Sectional and clinic anatomy Transport and storage of fats Synthesis, transport and excretion of cholesterol Liver nodules & neoplasms Disorders & neoplasms of the gallbladder Pathology of the exocrine pancreas Biosynthesis of fatty acids Synthesis, transport and excretion of cholesterol Drug used in gastrointestinal disorders Digestion of proteins, enzymes in stomach and intestines, effects of hormones -
5 Liver, pancreas Biosynthesis of fatty acids Transamination, oxidative deamination Utilization of carbon skeletons of amino acids in citric acid cycle Metabolism of histidine, lysine, hydroxylysine and aromatic amino acids Metabolism of serine, alanine, cysteine, methionine, threonine and glycine Acute and Chronic Liver Diseases Ascites Symptoms, Causes, Diagnosis (Portal Venous System and Portal Hypertension/non-portal ascites) Pancreatitis (Acute / Chronic) Antihelmintic drugs Determination of HDL-cholesterol Metabolism of branched chain amino acids, aspartate, asparagine, glutamate, glutamine, proline, hydroxyproline, arginine Transaminases Abdominal pain Inherited gastrointestinal tract diseases Urea cycle, its integration with citric acid cycle Regulation of urea cycle and metabolic disorders -
6 Hepatoxic effects of drugs Urea determination Determination of bilirubin and urobilinogen Determination of uric acid Emergency surgery in gastrointestinal system, Study for Final exam and Final exam -

Sources

Course Book 1. Clinical Neurology and Neuroanatomy: A Localization-Based Approach (1st Edition); Aaron Berkowitz; McGraw-Hill, 2017.
2. Gray’s Anatomy for Students (3rd Edition); Richard L. Drake, A. Wayne Vogl, Adam W. M. Mitchell; Churchill Livingston Elsevier, Philadelphia, 2015.
3. Guyton and Hall Textbook of Medical Physiology (13th Edition); John E. Hall; Elsevier, Philadelphia, 2016.
4. Histology: A Text and Atlas With Correlated Cell and Molecular Biology (7th Edition); Micheal H. Ross, Wojciech Pawlina; Lippincott Williams & Wilkins, 2015.
5. Kaplan and Sadock's Comprehensive Textbook of Psychiatry (10th Edition); Benjamin J. Sadock, Virginia Alcott Sadock, Pedro Ruiz; Lippincott Williams & Wilkins, Philadelphia, 2017.
6. Medical Microbiology (7th Edition); Patrick Murray, Ken Rosenthal, Michael Pfaller; Elsevier Saunders, Philadelphia, 2013.
7. Molecular and Cellular Biophysics; Meyer B. Jackson; Cambridge University Press, Cambridge, 2006.
8. Robbins Basic Pathology (10th Edition); Vinay Kumar, Abul K. Abbas, Jon C. Aster; Elsevier Saunders, Philadelphia, 2018.
9. The Developing Human: Clinically Oriented Embryology (10th Edition); Keith L. Moore, T. V. N. Persaud, Mark G. Torchia; Elsevier, Philadelphia, 2015.
10. Medical Microbiology (9th Edition); Patrick Murray, Ken Rosenthal, Michael Pfaller; Elsevier Saunders, Philadelphia, 2020.
11. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. John Bennett Raphael Dolin Martin J. Blaser. 9 th edition., 2019
12. Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e, McGraw-Hill Education, 2019

Evaluation System

Requirements Number Percentage of Grade
Attendance/Participation - -
Laboratory 15 20
Application - -
Field Work - -
Special Course Internship - -
Quizzes/Studio Critics - -
Homework Assignments - -
Presentation - -
Project - -
Report - -
Seminar - -
Midterms Exams/Midterms Jury - -
Final Exam/Final Jury 1 80
Toplam 16 100
Percentage of Semester Work
Percentage of Final Work 100
Total 100

Course Category

Core Courses X
Major Area Courses
Supportive Courses
Media and Managment Skills Courses
Transferable Skill Courses

The Relation Between Course Learning Competencies and Program Qualifications

# Program Qualifications / Competencies Level of Contribution
1 2 3 4 5
1 Integrates and utilizes the information, skills, and approaches obtained from basic, clinical, and medical sciences, behavioral sciences, and social sciences when offering healthcare services. X
2 Offers healthcare services to patients with a biopsychosocial approach where the sociodemographic and sociocultural backgrounds of these individuals are taken into consideration, focusing on the universal human values, ethical principles, and professional duties; without exercising discrimination on the basis of language, religion, race, or sex. X
3 Aims to protect, improve, and develop individual and public health when offering healthcare services. X
4 Performs the necessary studies in sustaining and improving health, taking into the individual, public, social, and environmental factors to affect it. X
5 Trains healthy individuals/ patients, their relatives, and other healthcare workers in healthcare upon determining the features, requirements, and expectations of their target audience. X
6 Exercises a safe, rational, and effective approach in the procedures of prevention, diagnosis, treatment, follow-up, and rehabilitation; while offering healthcare services. X
7 Implements interventional and/or non-interventional practices in a way that is safe and effective for patients during the procedures of diagnosis, treatment, follow-up, and rehabilitation. X
8 Offers healthcare services taking into account the health and safety of patients and employees. X
9 Takes the regional and global changes in physical and socioeconomic settings to affect health, as well as the changes in the individual features and behaviors of patients referring to them into account, while offering healthcare. X
10 Takes the good medical practices into account while performing their duties. X
11 Undertakes the tasks and duties within the framework of their professional ethical rules, as well as their legal rights and duties. X
12 Stands for the improvements in the manner in which healthcare services are offered, taking into account the concepts of social reliability and social duty, in an effort to protect and improve individual and public health. X
13 Evaluates the effects of health policies and healthcare practices on public health indicators, and, where required, amends their evaluation on the grounds of scientific and social needs; in an effort to help improve the quality of healthcare services. X
14 Leads their healthcare team while offering healthcare services, in a participative, and collaborative manner. X
15 Establishes positive relationships within their healthcare team; and where needed, easily adapts to various positions among their team. X
16 Exercises effective communication with patients, the relatives of patients, healthcare professionals, and groups from other professions, as well as institutions and organizations. X
17 Plans and conducts scientific studies on the society to which they serve, and use the results of these, or those from other studies, to benefit the society. X
18 Accesses the current literature on their profession, and evaluates them with a critical approach. X
19 Chooses the correct sources of learning to improve the healthcare services that they offer, and regulates their own learning process. X
20 Demonstrates the skills of obtaining and evaluating new information, integrating newer pieces of information with their current ones, as well as adapting to changing conditions throughout their professional life. X

ECTS/Workload Table

Activities Number Duration (Hours) Total Workload
Course Hours (Including Exam Week: 16 x Total Hours) 6 15 90
Laboratory 6 4 24
Application 2 1 2
Special Course Internship
Field Work
Study Hours Out of Class 6 15 90
Presentation/Seminar Prepration 1 6 6
Project
Report
Homework Assignments
Quizzes/Studio Critics
Prepration of Midterm Exams/Midterm Jury
Prepration of Final Exams/Final Jury 6 14 84
Total Workload 296